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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Diz-Kucukkay, Reyhan | - |
dc.date.accessioned | 2015-11-30T04:01:13Z | - |
dc.date.available | 2015-11-30T04:01:13Z | - |
dc.date.issued | 2013 | - |
dc.identifier.uri | http://220.231.117.85:8000/handle/DHKTYTHD_123/372 | - |
dc.description.abstract | Inherited platelet disorders (IPDs) are a heterogeneous group of diseases affecting platelet production, morphology, and function. The degree of thrombocytopenia and functional abnormality of platelets determines the clinical manifestations. Although severe deficiencies may cause excessive bleeding beginning in early childhood, most of IPDs have mild bleeding tendencies and therefore are not always easy to distinguish from acquired platelet disorders. The diagnosis of IPD may require extensive laboratory investigation, because current routine laboratory tests are not satisfactory for differential diagnosis in some cases, and most of the specific tests are not readily available in many countries. This review summarizes the classification and clinical and molecular characteristics of known IPDs, including Bernard-Soulier syndrome and Glanzmann thrombasthenia, with a focus on current challenges in the laboratory diagnosis and management of bleeding in these patients. | vi |
dc.language.iso | en | vi |
dc.publisher | American Society of Hematology | vi |
dc.title | Inherited platelet disorders including Glanzmann thrombasthenia and Bernard-Soulier syndrome | vi |
dc.type | Article | vi |
Appears in Collections | Huyết học = Hematology |
Files in This Item:
File | Description | Size | Format | |
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Hematology-2013-Diz-Küçükkaya-268-75.pdf Restricted Access | 334.73 kB | Adobe PDF | Request Item |
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